Publications & Featured publication

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We will feature one set of publications periodically and explore use of our solutions in enabling new discoveries.

Featured Publications

Two featured publications by IGB scientists on K-Ras structure for cancer therapy development and C. haemolyticum strain discovery using NGS.

IGB Publications

1. Lead identification for the K-Ras protein: virtual screening and combinatorial fragment-based approaches.
Pathan AA, Panthi B, Khan Z, Koppula PR, Alanazi MS, Sachchidanand, Parine NR, Chourasia M. Onco Targets Ther. 2016 May 2;9: 2575-84. doi: 10.2147/OTT.S99671. eCollection 2016.
Erratum in: Onco Targets Ther. 2017 Apr 28;10: 2365.

2. The Use of Next-Generation Sequencing in the Identification of a Fastidious Pathogen: A Lesson From a Clinical Setup

Saeb AT, Abouelhoda M, Selvaraju M, Althawadi SI, Mutabagani M, Adil M, Al Hokail A, Tayeb HT. Evol Bioinform Online. 2017 Feb 3;12:1176934316686072. doi: 10.1177/1176934316686072.

PubMed: 28469373

Publications

Toll-like receptor 6 expression, sequence variants, and their association with colorectal cancer risk.

Abdelhabib Semlali^1,2,Mikhlid Almutairi³, Akbar Ali Khan Pathan^2,6, Arezki Azzi⁷, Narasimha Reddy Parine², Abdullah AlAmri², Maha Arafah⁴, Abdulrahman M Aljebreen⁵, Othman alharbi⁵, Majid A Almadi⁵, Nahla Ali Azzam⁵, Mohammad Alanazi² and Mahmoud Rouabhia¹

A multi-disciplinary perspective on emergent and future innovations in peer review.

Tennant JP, Dugan JM, Graziotin D, Jacques DC, Waldner F, Mietchen D, Elkhatib Y, B Collister L, Pikas CK, Crick T, Masuzzo P, Caravaggi A, Berg DR, Niemeyer KE, Ross-Hellauer T, Mannheimer S, Rigling L, Katz DS, Greshake Tzovaras B, Pacheco-Mendoza J, Fatima N, Poblet M, Isaakidis M, Irawan DE, Renaut S, Madan CR, Matthias L, Nørgaard Kjær J, O’Donnell DP, Neylon C, Kearns S, Selvaraju M, Colomb J.

Version 3. F1000Res. 2017 Jul 20 [revised 2017 Jan 1]; 6:1151. doi: 10.12688/f1000research.12037.3. eCollection 2017. Review.

PubMed: 29188015

Genome sequencing and analysis of the first spontaneous Nanosilver resistant bacterium Proteus mirabilis strain SCDR1.

Saeb ATM, Al-Rubeaan KA, Abouelhoda M, Selvaraju M, Tayeb HT.

Antimicrob Resist Infect Control. 2017 Nov 23;6:119. doi: 10.1186/s13756-017-0277-x. e Collection 2017.

PubMed: 29204271

The hOGG1 Ser326Cys Gene Polymorphism and Breast Cancer Risk in Saudi Population.

Alanazi M, Pathan AAK, Shaik JP, Alhadheq A, Khan Z, Khan W, Al Naeem A, Parine NR.

Pathol Oncol Res. 2017 Jul; 23(3):525-535. doi: 10.1007/s12253-016-0146-6. Epub 2016 Nov 7.

PubMed: 27822728

Association of DNA Repair Gene APE1 Asp148Glu Polymorphism with Breast Cancer Risk.

AlMutairi F, Pathan AA, Alanazi M, Shalaby M, Alabdulkarim HA, Alamri A, Al Naeem A, Elrobh M, Shaik JP, Khan W, Khan Z, Parine NR.

Dis Markers. 2015; 2015:869512. doi: 10.1155/2015/869512. Epub 2015 Jul 16.

PubMed: 26257461

The Arabian camel Camelus dromedarius heat shock protein 90α: cDNA cloning, characterization and expression

Saeed H, Shalaby M, Embaby A, Ismael M, Pathan A, Ataya F, Alanazi M, Bassiouny K.

Int J Biol Macromol. 2015 Nov; 81:195-204. doi: 10.1016/j.ijbiomac.2015.07.058. Epub 2015 Jul 31.

PubMed: 26234578