Reproductive Health Research Using Next-Generation Sequencing

NGS Solutions for Reproductive Health Research | Ion Torrent Sequencing

Reproductive Health Research Using Next-Generation Sequencing

Overview:

Understanding risk factors for inherited genetic disorders is an important step in evaluating reproductive options. Expanded carrier screening (ECS) research and preimplantation genetic testing (PGT) offer critical insights that may increase probability of success for future pregnancies and healthier future generations.

Next-generation sequencing (NGS) has revolutionized reproductive health research with a high-throughput technology for rapidly sequencing DNA, with high accuracy. NGS has expanded both our menu of known genetic variants and our capacity to identify them. Ion Torrent NGS solutions deliver scalable, precise sequencing to better support reproductive health outcomes.

Workflow: 

  • Embryo Culture
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ProductsDescription
Embryo Culture 
Biosafety CabinetHerasafe 2030i
IncubatorsVIOS  IDX 160i
MicroscopeEVOS M Series
Cryogenic StorageCryomed Systems

 

  • Sample Preparation
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ProductsDescription
General Lab Instruments 
Multichannel pipettesThermo Scientific™ F1-ClipTip™ multichannel pipettes
Magnet systemDynaMag™-96 Side Magnet or 
MagMAX™ Pure Bind Beads 
Thermal cyclerVeritiPro™ Thermal Cycler, 96-well
Real-time PCRQuantStudio™ 5 Real-Time PCR System
Plate centrifugeThermo Scientific™ Megafuge™ 8 Small Benchtop Centrifuge Series
E-Gel Power Snap or Power Snap Plus Electrophoresis SystemInvitrogen™ E-Gel™ Power Snap Plus Electrophoresis Systems
Invitrogen™ Qubit™ Flex FluorometerQubit™ Flex Fluorometers
Automated extractorsApplied Biosystems™ KingFisher™ Apex Purification System

 

  • Analyze Your Sample

 

ProductsDescription
Sequencing Platforms 
NGS PlatformIon GeneStudio™ S5 System
Sample Prep and AutomationIon Chef™ Instrument
Analysis ServerIon Reporter™ Server System
Genexus Integrated SequencerGenexus™ Integrated Sequencer
SeqStudio 8 Flex Genetic AnalyzerApplied Biosystems™ SeqStudio™ 8 Flex Genetic Analyzer

 

ProductsDescription
Storage 
Fridge and freezerThermo Scientific™ convertible refrigerator/freezer
FreezerThermo Scientific™ convertible refrigerator/freezer
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