NGS Solutions for Reproductive Health Research | Ion Torrent Sequencing
Overview:
Understanding risk factors for inherited genetic disorders is an important step in evaluating reproductive options. Expanded carrier screening (ECS) research and preimplantation genetic testing (PGT) offer critical insights that may increase probability of success for future pregnancies and healthier future generations.
Next-generation sequencing (NGS) has revolutionized reproductive health research with a high-throughput technology for rapidly sequencing DNA, with high accuracy. NGS has expanded both our menu of known genetic variants and our capacity to identify them. Ion Torrent NGS solutions deliver scalable, precise sequencing to better support reproductive health outcomes.
Workflow:
| Products | Description |
| Embryo Culture | |
| Biosafety Cabinet | Herasafe 2030i |
| Incubators | VIOS IDX 160i |
| Microscope | EVOS M Series |
| Cryogenic Storage | Cryomed Systems |
| Products | Description |
| General Lab Instruments | |
| Multichannel pipettes | Thermo Scientific™ F1-ClipTip™ multichannel pipettes |
| Magnet system | DynaMag™-96 Side Magnet or MagMAX™ Pure Bind Beads |
| Thermal cycler | VeritiPro™ Thermal Cycler, 96-well |
| Real-time PCR | QuantStudio™ 5 Real-Time PCR System |
| Plate centrifuge | Thermo Scientific™ Megafuge™ 8 Small Benchtop Centrifuge Series |
| E-Gel Power Snap or Power Snap Plus Electrophoresis System | Invitrogen™ E-Gel™ Power Snap Plus Electrophoresis Systems |
| Invitrogen™ Qubit™ Flex Fluorometer | Qubit™ Flex Fluorometers |
| Automated extractors | Applied Biosystems™ KingFisher™ Apex Purification System |
| Products | Description |
| Sequencing Platforms | |
| NGS Platform | Ion GeneStudio™ S5 System |
| Sample Prep and Automation | Ion Chef™ Instrument |
| Analysis Server | Ion Reporter™ Server System |
| Genexus Integrated Sequencer | Genexus™ Integrated Sequencer |
| SeqStudio 8 Flex Genetic Analyzer | Applied Biosystems™ SeqStudio™ 8 Flex Genetic Analyzer |
| Products | Description |
| Storage | |
| Fridge and freezer | Thermo Scientific™ convertible refrigerator/freezer |
| Freezer | Thermo Scientific™ convertible refrigerator/freezer |
