High-Resolution Spatial Transcriptomics Without Targeted Gene Panels
Understand not just which genes are expressed, but where they are expressed within the tissue.
The Seeker Spatial Mapping Kit enables high-resolution, whole-transcriptome spatial mapping of fresh frozen tissue sections at 10 μm resolution. By capturing RNA on a densely packed layer of spatially indexed beads, Seeker preserves the spatial context of gene expression and reconstructs it into a continuous spatial transcriptome map.
Unlike targeted spatial methods that require predefined gene panels, Seeker captures polyadenylated RNA without restricting discovery to a predetermined set of targets. This allows researchers to investigate known biology while also discovering unexpected genes, pathways, cell populations, and spatial relationships.
Why Choose Seeker?
Whole-Transcriptome Discovery
Capture unbiased transcriptome-wide information without predesigning gene panels or limiting your experiment to a predefined set of targets.
Single-Cell-Scale Resolution
With 10 μm spatial resolution, Seeker enables researchers to investigate gene expression at single-cell scale and explore cellular organization within complex tissues.
Works Across Organisms
Use the same workflow across a broad range of organisms and tissue types. Fresh frozen samples from different species can be analyzed without tissue permeabilization optimization.
No Specialized Instrumentation
Seeker fits into existing molecular biology and next-generation sequencing workflows, helping laboratories access spatial transcriptomics without investing in dedicated spatial imaging instrumentation.
Why Is Seeker Important for Your Research?
Buy Seeker when your research question depends on understanding the relationship between gene expression and tissue location.
Seeker can help researchers:
Identify spatially distinct cell populations
Discover gene expression patterns across tissue regions
Study cell–cell and cell–environment interactions
Investigate disease-associated tissue changes
Characterize developmental processes
Explore tumor and immune microenvironments
Study neuroscience and tissue architecture
Investigate plant and animal biology
Discover spatially variable genes without restricting the experiment to a predefined panel
Because the assay is whole-transcriptome, researchers can preserve flexibility for discoveries that were not anticipated when the experiment was designed.
Key Benefits:
Whole-Transcriptome Profiling
Capture unbiased gene expression across the whole transcriptome without being restricted to predetermined gene panels.
10 μm Spatial Resolution
Achieve single-cell-scale resolution to investigate detailed gene expression patterns and tissue organization.
Fresh Frozen Tissue Compatibility
Analyze fresh frozen tissue samples across a broad range of organisms and research applications.
No Specialized Hardware
Integrate Seeker into standard molecular biology and next-generation sequencing workflows without requiring dedicated spatial instrumentation.
Flexible Tile Formats
Choose the format that fits your research needs with 3 × 3 mm and 10 × 10 mm tile options for different tissue sizes and regions of interest.
Integrated Bioinformatics
Transform sequencing data into spatial gene expression maps using Seeker's bioinformatics workflow for streamlined downstream analysis.
Species-Agnostic RNA Capture
Capture any polyadenylated RNA, enabling spatial transcriptomics across a wide range of organisms—not just human and mouse, but also non-model species.
Broad Tissue Applicability
Work across diverse tissue types without extensive permeabilization optimization, reducing assay development and troubleshooting when moving between samples.
Fast Time to Results
Generate sequencing-ready libraries in as little as one day, enabling a faster path from tissue sample to spatial transcriptomic data.
