Overview
The Thermo Scientific™ HID NIMBUS™ Presto is an integrated, high-throughput automation platform purpose-built for forensic DNA extraction and purification workflows. By combining magnetic bead–based purification with precision liquid handling, the system enables standardized, end-to-end processing from lysed samples to purified DNA with minimal manual intervention.
Designed for forensic laboratories handling diverse and challenging sample types, the platform improves consistency, reduces contamination risk, and delivers high-quality DNA suitable for downstream quantification and STR analysis.
Features
• Integrated platform combining KingFisher™ magnetic particle purification with Hamilton Microlab NIMBUS liquid handling
• Fully automated DNA extraction workflow from lysed samples to purified DNA
• Validated workflows aligned with SWGDAM guidelines for forensic applications
• Optimized compatibility with PrepFiler™ and PrepFiler™ BTA extraction chemistries
• Advanced CO-RE (Compressed O-Ring Expansion) pipetting for precise liquid handling and reduced contamination
• Robotic plate handling and tip comb transfer for hands-free operation
• Flexible throughput from 1 to 96 samples per run
• Efficient processing time with runs completed in under 90 minutes
Specifications
• Throughput: Up to 96 samples per run
• Volume Range: 50 µL to 5,000 µL
• Pipetting Channels: 4-channel independent liquid handling
• Purification Technology: Magnetic particle-based (KingFisher™ technology)
• Labware Compatibility: 96-well deep-well plates and multiple tube formats
• Interface: HID NIMBUS software with guided setup
• Compliance: SWGDAM and DNA Advisory Board (DAB) validated workflows
• Dimensions: 70.9 × 135.9 × 88.9 cm (W × D × H)
Applications
• Forensic DNA extraction and purification
• Processing of challenging forensic samples (bone, teeth, adhesive materials)
• STR analysis workflow preparation
• High-throughput forensic casework and database processing
Snapshot
• Technology: Magnetic bead-based purification integrated with automated liquid handling
• Workflow: Fully automated DNA extraction and purification
• Output: High-quality purified DNA suitable for qPCR and STR analysis
• Use Case: Forensic laboratories requiring validated, scalable, and contamination-controlled DNA extraction workflows
