Overview
The Applied Biosystems™ 3500 Series Genetic Analyzers are industry-standard capillary electrophoresis systems designed for high-precision DNA analysis in forensic and human identification (HID) laboratories. Available in both 8-capillary and 24-capillary configurations, these systems deliver robust performance for STR analysis, DNA sequencing, and fragment analysis workflows.
By integrating advanced electrophoresis technology with HID-optimized software and reagents, the platform enables a streamlined sample-to-result workflow, ensuring high confidence, reproducibility, and compliance in regulated laboratory environments.
Features
• Precision thermal control ensuring uniform capillary temperature for accurate fragment separation
• RFID-enabled consumable tracking for automated monitoring of usage, lot numbers, and expiry
• Long-life 505 nm solid-state laser with minimal maintenance requirements
• Pre-configured HID workflows optimized for STR analysis kits such as GlobalFiler™ and YFiler™ Plus
• Enhanced signal uniformity for consistent, reproducible results across runs and instruments
• 6-dye multiplexing capability enabling higher data output per sample
Specifications
• Configurations: 8-capillary (3500) and 24-capillary (3500xL) systems
• Capillary Count: 8 or 24 capillaries
• Laser: 505 nm solid-state
• Throughput: Up to ~280 samples/23 hours (3500) and ~840 samples/23 hours (3500xL)
• Voltage: Up to 20 kV
• Oven Temperature Range: 18°C to 70°C
• Dimensions: 61 cm (W) × 61 cm (D) × 72 cm (H)
• Polymer Compatibility: POP-4™, POP-6™, POP-7™
Applications
• Human identification and forensic DNA analysis (STR profiling)
• DNA sequencing and mutation analysis
• Fragment analysis including microsatellite and SNP studies
• Research workflows in genomics and applied biosciences
Technical Snapshot
• Technology: Capillary electrophoresis
• Workflow: Automated DNA separation and detection
• Output: High-resolution, reproducible DNA fragment data
• Use Case: Forensic, HID, and advanced genetic analysis laboratories
