Overview
High-Content Screening (HCS) / High-Content Analysis (HCA) systems integrate automated microscopy with advanced image analysis to enable simultaneous measurement of multiple cellular parameters. These platforms support high-throughput, unbiased phenotypic screening and quantitative single-cell analysis, making them essential for modern drug discovery and advanced cell biology research workflows.
Features
• Automated imaging combined with quantitative single-cell analysis
• Multiparametric readouts including morphology, intensity, and localization
• High-throughput screening with plate formats from 96 to 1536 wells
• Brightfield and multi-color fluorescence detection capabilities
• Integrated software for image acquisition, processing, and data analysis
• Compatibility with live-cell, fixed-cell, and 3D cell models
Applications
• Drug discovery and phenotypic screening
• Cell health, toxicity, and apoptosis studies
• Cell painting and morphological profiling
• Immuno-oncology and neuroscience research
• Stem cell and 3D organoid analysis
• High-throughput assay development
Technical Snapshot
• Technology: Automated fluorescence microscopy with advanced image analysis
• Throughput: Medium to ultra-high (plate-based automation)
• Multiplexing: Multi-parameter analysis per cell using multi-channel imaging
• Formats: Slides and multi-well plates (6–1536 wells)
• Software: Integrated platforms for image analysis and quantitative data extraction
Available Models
• CellInsight CX5 HCS Platform – Compact system for routine high-content imaging
• CellInsight CX7 HCS Platform – Advanced system with enhanced sensitivity and live-cell capability
• CellInsight CX7 LZR Pro / LED Pro – High-end systems with laser/LED illumination and advanced automation
• ArrayScan HCS System – Established platform for automated fluorescence-based cell analysis
