Overview:
IGB offers Twist Precision Dx solutions for whole exome sequencing, providing an IVDR-compliant workflow for high-quality library preparation and target enrichment. The Twist Precision Exome Dx Kit delivers a complete, validated solution that integrates enzymatic fragmentation, library preparation, and exome target enrichment into a streamlined workflow for next-generation sequencing (NGS) applications.
This product suite includes modular and flexible components that can be used individually or as a complete solution, enabling laboratories to adapt workflows based on their requirements. Designed for use with high-quality genomic DNA from human samples such as whole blood, these solutions ensure reliable performance and compatibility with clinical and research environments.
The complete solution includes:
• Twist Precision Prep and Enrichment Dx Kit – Reagents for enzymatic fragmentation, library preparation, and enrichment
• Twist Precision Exome Dx Panel – Targeted capture probes for exome enrichment
• Twist Precision Exome Dx Kit – Integrated solution combining preparation, enrichment, and exome capture
Features:
Comprehensive Coverage
• >97% coverage across CCDS, RefSeq, Gencode, and Ensembl v101 databases
• Expanded coverage of mitochondrial genome
Reliable Performance
• Consistent yield from high-complexity libraries
• Uniform enrichment across target regions
• Sequence-verified probes for reliable results
Flexible
• Panel-agnostic workflow with Twist Precision Prep and Enrichment Dx Kit
• Standalone Exome Dx Panel integrates with existing workflows
• Complete kit provides fully validated end-to-end workflow
IVDR Compliant
• Designed to meet EU IVDR 2017/746 requirements
• Ensures quality, traceability, and regulatory compliance
